The Diethylstilbestrol Legacy: A Powerful Case Against Intervention in Uncomplicated Pregnancy.
نویسندگان
چکیده
aEpidemiology and Biostatistics Program, Division of Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland; bDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts; and cGeisel School of Medicine at Dartmouth and the Hood Center for Children and Families, Lebanon, New Hampshire
منابع مشابه
Primary Clear Cell Carcinoma with no Diethylstilbestrol Exposure; Case Series
One of the rare neoplasms of cervix uteri and vagina is clear cell carcinoma; mostly in patients with a positive past medical history of intrauterine diethylstilbestrol (DES) exposure which reveals the importance of other unknown risk factors of gynecologic neoplasms. 2 Asian women referred to the gynecology-oncology department. The first one came with a complaint of prolonged vaginal discharge...
متن کاملNon-Diethylstilbestrol-Associated Primary Clear Cell Carcinoma of the Vagina: Two Case Reports with Immunohistochemical Studies and Literature Review
Primary clear cell adenocarcinomas most commonly involve the genitourinary system, including the vagina. Previously, primary clear cell adenocarcinomas of the vagina have been discussed within the context of prenatal exposure to diethylstilbestrol. Due to its widely proven role in the development of this carcinoma, administration of diethylstilbestrol is prohibited. We present two cases of non-...
متن کاملIn Vivo Study of Diethylstilbestrol Teratogenicity on Mouse Embryo
Diethylstilbestrol (DES) was widely used in the past, as the morning after contraception, but its application became extremely limited due to several complications including delayed clear cell adenocarcinoma in female infants. However, the use of DES increased during the past decade for hormone replacement therapy. The aim of this study was to investigate possible teratogenicity of this...
متن کاملبررسی رابطه تعداد گلبول‌های قرمز هسته‌دار خون بند ناف نوزادان ترم با مایع آمنیوتیک آغشته به مکونیوم
Introduction & Objective: Considering the incidence of meconium in amniotic fluid and its complications, this study was based on indirect reports which pointed out the relationship between nucleated red blood cell (nRbC) (as a marker of chronic hypoxia) and Meconium – stained Amniotic Fluid (MSAF) in term newborns. Materials & Methods: In order to determine this relationship more accurately wo...
متن کاملبررسی رابطه گلبول های قرمز هسته دار خون بند ناف نوزاد ترم با مایع آمنیوتیک آغشته به مکونیوم
Considering the incidence of meconium-stained amniotic fluid (MSAF) in newborns and its complications, and also based on indirect reports pointing out relationship between nucleated red blood cell (nRBC), as a marker of chronic hypoxia, and MSAF in term newborns, and in order to determine this relationship more accurately, this study was done on women with uncomplicated singleton term pregnancy...
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ورودعنوان ژورنال:
- Pediatrics
دوره 138 Suppl 1 شماره
صفحات -
تاریخ انتشار 2016